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A novel anti-EGFR monoclonal antibody (EMab-17) exerts antitumor activity against oral squamous cell carcinomas via antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity

The epidermal growth factor receptor (EGFR) is a member of the human epidermal growth factor receptor (HER) family of receptor tyrosine kinases; it is a transmembrane receptor involved in cell growth and differentiation. EGFR homodimers or heterodimers in combination with other HER members, such as...

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Detalles Bibliográficos
Autores principales: Takei, Junko, Kaneko, Mika Kato, Ohishi, Tomokazu, Kawada, Manabu, Harada, Hiroyuki, Kato, Yukinari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068343/
https://www.ncbi.nlm.nih.gov/pubmed/32218834
http://dx.doi.org/10.3892/ol.2020.11384