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Construction of Glycometabolism- and Hormone-Related lncRNA-Mediated Feedforward Loop Networks Reveals Global Patterns of lncRNAs and Drug Repurposing in Gestational Diabetes

Gestational diabetes mellitus (GDM) is a condition associated with the onset of abnormal glucose tolerance during pregnancy. Long non-coding RNAs (lncRNAs), microRNAs (miRNAs), and genes can form lncRNA-mediated feedforward loops (lnc-FFLs), which are functional network motifs that regulate a wide r...

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Detalles Bibliográficos
Autores principales: Fu, Xuelian, Cong, Huifang, Zhao, Shuyu, Li, Yan, Liu, Tianyi, Sun, Yuhong, Lv, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068675/
https://www.ncbi.nlm.nih.gov/pubmed/32210913
http://dx.doi.org/10.3389/fendo.2020.00093