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Reduced Protumorigenic Tumor-Associated Macrophages With Statin Use in Premalignant Human Lung Adenocarcinoma

BACKGROUND: Statins have anticancer properties by acting as competitive inhibitors of the mevalonate pathway. They also have anti-inflammatory activity, but their role in suppressing inflammation in a cancer context has not been investigated to date. METHODS: We have analyzed the relationship betwee...

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Detalles Bibliográficos
Autores principales: Al Dujaily, Esraa, Baena, Juvenal, Das, Madhumita, Sereno, Marco, Smith, Claire, Kamata, Tamihiro, Officer, Leah, Pritchard, Catrin, Le Quesne, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068793/
https://www.ncbi.nlm.nih.gov/pubmed/32190817
http://dx.doi.org/10.1093/jncics/pkz101