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Reduced Protumorigenic Tumor-Associated Macrophages With Statin Use in Premalignant Human Lung Adenocarcinoma
BACKGROUND: Statins have anticancer properties by acting as competitive inhibitors of the mevalonate pathway. They also have anti-inflammatory activity, but their role in suppressing inflammation in a cancer context has not been investigated to date. METHODS: We have analyzed the relationship betwee...
Autores principales: | Al Dujaily, Esraa, Baena, Juvenal, Das, Madhumita, Sereno, Marco, Smith, Claire, Kamata, Tamihiro, Officer, Leah, Pritchard, Catrin, Le Quesne, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068793/ https://www.ncbi.nlm.nih.gov/pubmed/32190817 http://dx.doi.org/10.1093/jncics/pkz101 |
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