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Accelerated immunosenescence in rheumatoid arthritis: impact on clinical progression
Patients with rheumatoid arthritis (RA) develop features of accelerated ageing, including immunosenescence. These changes include decreased thymic functionality, expansion of late-differentiated effector T cells, increased telomeric attrition, and excessive production of cytokines (senescence-associ...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068869/ https://www.ncbi.nlm.nih.gov/pubmed/32190092 http://dx.doi.org/10.1186/s12979-020-00178-w |