Adenovirus-mediated anti-AEG-1 ScFv expression driven by stathmin promoter inhibits tumor growth in cervical cancer

BACKGROUND: Astrocyte-elevated gene-1 (AEG-1) is over-expressed in many cancer cells and has multiple key functions in tumor initiation and progression. Currently, targeted-AEG-1 siRNA is one of the most common techniques to down-regulate AEG-1 expression, but the lack of tumor specificity and avail...

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Detalles Bibliográficos
Autores principales: Long, Min, Lin, Fang, Wang, Xi, Chen, Xi, Liu, Li, Zhang, Huizhong, Dong, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068931/
https://www.ncbi.nlm.nih.gov/pubmed/32190003
http://dx.doi.org/10.1186/s12935-020-1159-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068931/
https://www.ncbi.nlm.nih.gov/pubmed/32190003
http://dx.doi.org/10.1186/s12935-020-1159-5

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