Alteration in the sensitivity to crizotinib by Na(+)/H(+) exchanger regulatory factor 1 is dependent to its subcellular localization in ALK-positive lung cancers

BACKGROUND: Na(+)/H(+) exchanger regulatory factor 1 (NHERF1) is an important scaffold protein participates in the modulation of a variety of intracellular signal pathways. NHERF1 was able to enhance the effects of chemo-drugs in breast and cervical cancer cells. Anaplastic lymphoma kinase (ALK) fus...

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Detalles Bibliográficos
Autores principales: Yang, Fenglian, Hu, Mu, Chang, Siyuan, Huang, Jing, Si, Yang, Wang, Jinghui, Cheng, Shan, Jiang, Wen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068933/
https://www.ncbi.nlm.nih.gov/pubmed/32164629
http://dx.doi.org/10.1186/s12885-020-6687-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068933/
https://www.ncbi.nlm.nih.gov/pubmed/32164629
http://dx.doi.org/10.1186/s12885-020-6687-9

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