An immune-centric exploration of BRCA1 and BRCA2 germline mutation related breast and ovarian cancers

BACKGROUND: BRCA1/2 germline mutation related cancers are candidates for new immune therapeutic interventions. This study was a hypothesis generating exploration of genomic data collected at diagnosis for 19 patients. The prominent tumor mutation burden (TMB) in hereditary breast and ovarian cancers...

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Detalles Bibliográficos
Autores principales: Przybytkowski, Ewa, Davis, Thomas, Hosny, Abdelrahman, Eismann, Julia, Matulonis, Ursula A., Wulf, Gerburg M., Nabavi, Sheida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068944/
https://www.ncbi.nlm.nih.gov/pubmed/32164626
http://dx.doi.org/10.1186/s12885-020-6605-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068944/
https://www.ncbi.nlm.nih.gov/pubmed/32164626
http://dx.doi.org/10.1186/s12885-020-6605-1

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