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A DLG2 deficiency in mice leads to reduced sociability and increased repetitive behavior accompanied by aberrant synaptic transmission in the dorsal striatum

BACKGROUND: DLG2, also known as postsynaptic density protein-93 (PSD-93) or chapsyn-110, is an excitatory postsynaptic scaffolding protein that interacts with synaptic surface receptors and signaling molecules. A recent study has demonstrated that mutations in the DLG2 promoter region are significan...

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Detalles Bibliográficos
Autores principales: Yoo, Taesun, Kim, Sun-Gyun, Yang, Soo Hyun, Kim, Hyun, Kim, Eunjoon, Kim, Soo Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069029/
https://www.ncbi.nlm.nih.gov/pubmed/32164788
http://dx.doi.org/10.1186/s13229-020-00324-7