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A distinct molecular mutational profile and its clinical impact in essential thrombocythemia and primary myelofibrosis patients
BACKGROUND: Classical MPNs including ET and PMF have a chronic course and potential for leukaemic transformation. Timely diagnosis is obligatory to ensure appropriate management and positive outcomes. The aim of this study was to determine the mutational profile, clinical characteristics and outcome...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069043/ https://www.ncbi.nlm.nih.gov/pubmed/32164591 http://dx.doi.org/10.1186/s12885-020-6700-3 |