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Stepwise targeting and responsive lipid-coated nanoparticles for enhanced tumor cell sensitivity and hepatocellular carcinoma therapy

Rationale: Antitumor drug delivery faces multiple barriers that require consecutively achieving tumor targeting, selective cellular uptake and sufficient intracellular drug dosage. Methods: Herein, we designed smart nanoparticles (GPDC-MSNs) that can accumulate stepwise in tumor tissues, selectively...

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Detalles Bibliográficos
Autores principales: Li, Ying, Miao, Yunqiu, Chen, Mingshu, Chen, Xi, Li, Feifei, Zhang, Xinxin, Gan, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069070/
https://www.ncbi.nlm.nih.gov/pubmed/32206118
http://dx.doi.org/10.7150/thno.42008