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Novel calreticulin-nanoparticle in combination with focused ultrasound induces immunogenic cell death in melanoma to enhance antitumor immunity

Rationale: Some studies have shown that the local activation of immunogenic cell death (ICD) by upregulating calreticulin (CRT) expression in solid tumors can improve antitumor effects. Although a promising approach, a key current challenge in ICD tumor therapy is the absence of a clinically transla...

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Detalles Bibliográficos
Autores principales: Sethuraman, Sri Nandhini, Singh, Mohit Pratap, Patil, Girish, Li, Shitao, Fiering, Steven, Hoopes, P. Jack, Guha, Chandan, Malayer, Jerry, Ranjan, Ashish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069083/
https://www.ncbi.nlm.nih.gov/pubmed/32206098
http://dx.doi.org/10.7150/thno.42243