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ROCK inhibitor increases proacinar cells in adult salivary gland organoids

Salisphere-derived adult epithelial cells have been used to improve saliva production of irradiated mouse salivary glands. Importantly, optimization of the cellular composition of salispheres could improve their regenerative capabilities. The Rho Kinase (ROCK) inhibitor, Y27632, has been used to inc...

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Detalles Bibliográficos
Autores principales: Koslow, Matthew, O’Keefe, Kevin J, Hosseini, Zeinab F., Nelson, Deirdre A., Larsen, Melinda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069099/
https://www.ncbi.nlm.nih.gov/pubmed/31731180
http://dx.doi.org/10.1016/j.scr.2019.101608