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Accurately estimating the length distributions of genomic micro-satellites by tumor purity deconvolution
BACKGROUND: Genomic micro-satellites are the genomic regions that consist of short and repetitive DNA motifs. Estimating the length distribution and state of a micro-satellite region is an important computational step in cancer sequencing data pipelines, which is suggested to facilitate the downstre...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069170/ https://www.ncbi.nlm.nih.gov/pubmed/32164528 http://dx.doi.org/10.1186/s12859-020-3349-5 |