Завантаження...
Pre-existing inflammatory immune microenvironment predicts the clinical response of vulvar high-grade squamous intraepithelial lesions to therapeutic HPV16 vaccination
BACKGROUND: Vulvar high-grade squamous intraepithelial lesion (vHSIL) is predominantly induced by high-risk human papilloma virus type 16 (HPV16). In two independent trials, therapeutic vaccination against the HPV16 E6 and E7 oncoproteins resulted in objective partial and complete responses (PRs/CRs...
Автори: | , , , , , , , |
---|---|
Формат: | Online Стаття Текст |
Мова: | English |
Опубліковано: |
BMJ Publishing Group
2020
|
Предмети: | |
Онлайн доступ: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069269/ https://www.ncbi.nlm.nih.gov/pubmed/32169871 http://dx.doi.org/10.1136/jitc-2020-000563 |