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Potent STING activation stimulates immunogenic cell death to enhance antitumor immunity in neuroblastoma

BACKGROUND: Neuroblastoma (NB) is a childhood cancer for which new treatment options are needed. The success of immune checkpoint blockade in the treatment of adult solid tumors has prompted the exploration of immunotherapy in NB; however, clinical evidence indicates that the vast majority of NB pat...

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Detalles Bibliográficos
Autores principales: Wang-Bishop, Lihong, Wehbe, Mohamed, Shae, Daniel, James, Jamaal, Hacker, Benjamin C., Garland, Kyle, Chistov, Plamen P., Rafat, Marjan, Balko, Justin M., Wilson, John T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069313/
https://www.ncbi.nlm.nih.gov/pubmed/32169869
http://dx.doi.org/10.1136/jitc-2019-000282