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Testing Proximity of Genomic Regions to Transcription Start Sites and Enhancers Complements Gene Set Enrichment Testing

Large sets of genomic regions are generated by the initial analysis of various genome-wide sequencing data, such as ChIP-seq and ATAC-seq experiments. Gene set enrichment (GSE) methods are commonly employed to determine the pathways associated with them. Given the pathways and other gene sets (e.g.,...

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Detalles Bibliográficos
Autores principales: Lee, Christopher, Wang, Kai, Qin, Tingting, Sartor, Maureen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069355/
https://www.ncbi.nlm.nih.gov/pubmed/32211031
http://dx.doi.org/10.3389/fgene.2020.00199