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Expanding the utility of the dextran sulfate sodium (DSS) mouse model to induce a clinically relevant loss of intestinal barrier function

BACKGROUND: Inflammatory bowel disease (IBD) is a family of debilitating disorders that affects more than 1 million people in the United States. Many animal studies of IBD use a dextran sulfate sodium (DSS) mouse model of colitis that induces rapid and severe colitis symptoms. Although the typical s...

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Detalles Bibliográficos
Autores principales: Cochran, Kyle E., Lamson, Nicholas G., Whitehead, Kathryn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069414/
https://www.ncbi.nlm.nih.gov/pubmed/32195049
http://dx.doi.org/10.7717/peerj.8681