Not all therapeutic antibody isotypes are equal: the case of IgM versus IgG in Pertuzumab and Trastuzumab

The therapeutic potential of immunoglobulin M (IgM) is of considerable interest in immunotherapy due to its complement-activating and cell-agglutinating abilities. Pertuzumab and Trastuzumab are monoclonal antibodies used to treat human epidermal growth factor receptor 2 (HER2)-positive breast cance...

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Detalles Bibliográficos
Autores principales: Samsudin, Firdaus, Yeo, Joshua Yi, Gan, Samuel Ken-En, Bond, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069520/
https://www.ncbi.nlm.nih.gov/pubmed/32206268
http://dx.doi.org/10.1039/c9sc04722k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069520/
https://www.ncbi.nlm.nih.gov/pubmed/32206268
http://dx.doi.org/10.1039/c9sc04722k

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