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Global crotonylome reveals CDYL-regulated RPA1 crotonylation in homologous recombination–mediated DNA repair

Previously, we reported that chromodomain Y–like (CDYL) acts as a crotonyl–coenzyme A hydratase and negatively regulates histone crotonylation (Kcr). However, the global CDYL-regulated crotonylome remains unclear. Here, we report a large-scale proteomics analysis for protein Kcr. We identify 14,311...

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Detalles Bibliográficos
Autores principales: Yu, Huajing, Bu, Chen, Liu, Yuncheng, Gong, Tianyu, Liu, Xiaoping, Liu, Shumeng, Peng, Xiaojun, Zhang, Wenting, Peng, Yani, Yang, Jianguo, He, Lin, Zhang, Yu, Yi, Xia, Yang, Xiaohan, Sun, Luyang, Shang, Yongfeng, Cheng, Zhongyi, Liang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069697/
https://www.ncbi.nlm.nih.gov/pubmed/32201722
http://dx.doi.org/10.1126/sciadv.aay4697