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Single-cell mass cytometry reveals cross-talk between inflammation-dampening and inflammation-amplifying cells in osteoarthritic cartilage

Aging or injury leads to degradation of the cartilage matrix and the development of osteoarthritis (OA). Because of a paucity of single-cell studies of OA cartilage, little is known about the interpatient variability in its cellular composition and, more importantly, about the cell subpopulations th...

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Detalles Bibliográficos
Autores principales: Grandi, Fiorella Carla, Baskar, Reema, Smeriglio, Piera, Murkherjee, Shravani, Indelli, Pier Francesco, Amanatullah, Derek F., Goodman, Stuart, Chu, Constance, Bendall, Sean, Bhutani, Nidhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069698/
https://www.ncbi.nlm.nih.gov/pubmed/32201724
http://dx.doi.org/10.1126/sciadv.aay5352