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A reconstituted mammalian APC-kinesin complex selectively transports defined packages of axonal mRNAs
Through the asymmetric distribution of messenger RNAs (mRNAs), cells spatially regulate gene expression to create cytoplasmic domains with specialized functions. In neurons, mRNA localization is required for essential processes such as cell polarization, migration, and synaptic plasticity underlying...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069705/ https://www.ncbi.nlm.nih.gov/pubmed/32201729 http://dx.doi.org/10.1126/sciadv.aaz1588 |