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A reconstituted mammalian APC-kinesin complex selectively transports defined packages of axonal mRNAs

Through the asymmetric distribution of messenger RNAs (mRNAs), cells spatially regulate gene expression to create cytoplasmic domains with specialized functions. In neurons, mRNA localization is required for essential processes such as cell polarization, migration, and synaptic plasticity underlying...

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Detalles Bibliográficos
Autores principales: Baumann, Sebastian, Komissarov, Artem, Gili, Maria, Ruprecht, Verena, Wieser, Stefan, Maurer, Sebastian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069705/
https://www.ncbi.nlm.nih.gov/pubmed/32201729
http://dx.doi.org/10.1126/sciadv.aaz1588

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