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Dullard-mediated Smad1/5/8 inhibition controls mouse cardiac neural crest cells condensation and outflow tract septation

The establishment of separated pulmonary and systemic circulation in vertebrates, via cardiac outflow tract (OFT) septation, is a sensitive developmental process accounting for 10% of all congenital anomalies. Neural Crest Cells (NCC) colonising the heart condensate along the primitive endocardial t...

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Detalles Bibliográficos
Autores principales: Darrigrand, Jean-François, Valente, Mariana, Comai, Glenda, Martinez, Pauline, Petit, Maxime, Nishinakamura, Ryuichi, Osorio, Daniel S, Renault, Gilles, Marchiol, Carmen, Ribes, Vanessa, Cadot, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069721/
https://www.ncbi.nlm.nih.gov/pubmed/32105214
http://dx.doi.org/10.7554/eLife.50325