The mechanism and role of intracellular α-ketoglutarate reduction in hepatic stellate cell activation

Background: The activation of hepatic stellate cells (HSCs) plays a central role in liver fibrosis. α-ketoglutarate is a natural metabolite and previous studies have shown that increase in intracellular α-ketoglutarate can inhibit HSC activation. Aim: The aim of the present study is to determine the...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Jianjian, Jiang, Yueping, Sun, Xueguo, Liu, Xishuang, Liu, Fuguo, Song, Mingquan, Zhang, Lingyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069903/
https://www.ncbi.nlm.nih.gov/pubmed/32124915
http://dx.doi.org/10.1042/BSR20193385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069903/
https://www.ncbi.nlm.nih.gov/pubmed/32124915
http://dx.doi.org/10.1042/BSR20193385

Ejemplares similares