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The mechanism and role of intracellular α-ketoglutarate reduction in hepatic stellate cell activation

Background: The activation of hepatic stellate cells (HSCs) plays a central role in liver fibrosis. α-ketoglutarate is a natural metabolite and previous studies have shown that increase in intracellular α-ketoglutarate can inhibit HSC activation. Aim: The aim of the present study is to determine the...

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Detalles Bibliográficos
Autores principales:	Zhao, Jianjian, Jiang, Yueping, Sun, Xueguo, Liu, Xishuang, Liu, Fuguo, Song, Mingquan, Zhang, Lingyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2020
Materias:	Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069903/ https://www.ncbi.nlm.nih.gov/pubmed/32124915 http://dx.doi.org/10.1042/BSR20193385

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