Amyloid formation of bovine insulin is retarded in moderately acidic pH and by addition of short-chain alcohols

Protein aggregation and amyloid formation are associated with multiple human diseases, but are also a problem in protein production. Understanding how aggregation can be modulated is therefore of importance in both medical and industrial contexts. We have used bovine insulin as a model protein to ex...

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Detalles Bibliográficos
Autores principales: Bernson, David, Mecinovic, Almedina, Abed, Md Tuhin, Limé, Fredrik, Jageland, Per, Palmlöf, Magnus, Esbjörner, Elin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069927/
https://www.ncbi.nlm.nih.gov/pubmed/31901953
http://dx.doi.org/10.1007/s00249-019-01420-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069927/
https://www.ncbi.nlm.nih.gov/pubmed/31901953
http://dx.doi.org/10.1007/s00249-019-01420-0

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