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Amyloid formation of bovine insulin is retarded in moderately acidic pH and by addition of short-chain alcohols
Protein aggregation and amyloid formation are associated with multiple human diseases, but are also a problem in protein production. Understanding how aggregation can be modulated is therefore of importance in both medical and industrial contexts. We have used bovine insulin as a model protein to ex...
Autores principales: | Bernson, David, Mecinovic, Almedina, Abed, Md Tuhin, Limé, Fredrik, Jageland, Per, Palmlöf, Magnus, Esbjörner, Elin K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069927/ https://www.ncbi.nlm.nih.gov/pubmed/31901953 http://dx.doi.org/10.1007/s00249-019-01420-0 |
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