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Cholesteryl α-D-glucoside 6-acyltransferase enhances the adhesion of Helicobacter pylori to gastric epithelium

Helicobacter pylori, the most common etiologic agent of gastric diseases including gastric cancer, is auxotrophic for cholesterol and has to hijack it from gastric epithelia. Upon uptake, the bacteria convert cholesterol to cholesteryl 6′-O-acyl-α-D-glucopyranoside (CAG) to promote lipid raft cluste...

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Detalles Bibliográficos
Autores principales: Jan, Hau-Ming, Chen, Yi-Chi, Yang, Tsai-Chen, Ong, Lih-Lih, Chang, Chia-Chen, Muthusamy, Sasikala, Abera, Andualem Bahiru, Wu, Ming-Shiang, Gervay-Hague, Jacquelyn, Mong, Kwok-Kong Tony, Lin, Chun-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069968/
https://www.ncbi.nlm.nih.gov/pubmed/32170208
http://dx.doi.org/10.1038/s42003-020-0855-y