Cargando…
Cholesteryl α-D-glucoside 6-acyltransferase enhances the adhesion of Helicobacter pylori to gastric epithelium
Helicobacter pylori, the most common etiologic agent of gastric diseases including gastric cancer, is auxotrophic for cholesterol and has to hijack it from gastric epithelia. Upon uptake, the bacteria convert cholesterol to cholesteryl 6′-O-acyl-α-D-glucopyranoside (CAG) to promote lipid raft cluste...
Autores principales: | Jan, Hau-Ming, Chen, Yi-Chi, Yang, Tsai-Chen, Ong, Lih-Lih, Chang, Chia-Chen, Muthusamy, Sasikala, Abera, Andualem Bahiru, Wu, Ming-Shiang, Gervay-Hague, Jacquelyn, Mong, Kwok-Kong Tony, Lin, Chun-Hung |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069968/ https://www.ncbi.nlm.nih.gov/pubmed/32170208 http://dx.doi.org/10.1038/s42003-020-0855-y |
Ejemplares similares
-
Metabolic labelling of cholesteryl glucosides in Helicobacter pylori reveals how the uptake of human lipids enhances bacterial virulence
por: Jan, Hau-Ming, et al.
Publicado: (2016) -
Enhanced enzymatic production of cholesteryl 6ʹ-acylglucoside impairs lysosomal degradation for the intracellular survival of Helicobacter pylori
por: Muthusamy, Sasikala, et al.
Publicado: (2021) -
Roles of Cholesteryl-α-Glucoside Transferase and Cholesteryl Glucosides in Maintenance of Helicobacter pylori Morphology, Cell Wall Integrity, and Resistance to Antibiotics
por: Qaria, Majjid A., et al.
Publicado: (2018) -
Helicobacter pylori Cholesteryl α-Glucosides Contribute to Its Pathogenicity and Immune Response by Natural Killer T Cells
por: Ito, Yuki, et al.
Publicado: (2013) -
The acyltransferase PMAT1 malonylates brassinolide glucoside
por: Gan, Sufu, et al.
Publicado: (2021)