Engineering of an enhanced synthetic Notch receptor by reducing ligand-independent activation

Notch signaling is highly conserved in most animals and plays critical roles during neurogenesis as well as embryonic development. Synthetic Notch-based systems, modeled from Notch receptors, have been developed to sense and respond to a specific extracellular signal. Recent advancement of synNotch...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Zi-jie, Yu, Zi-yan, Cai, Yi-ming, Du, Rong-rong, Cai, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069970/
https://www.ncbi.nlm.nih.gov/pubmed/32170210
http://dx.doi.org/10.1038/s42003-020-0848-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069970/
https://www.ncbi.nlm.nih.gov/pubmed/32170210
http://dx.doi.org/10.1038/s42003-020-0848-x

Ejemplares similares