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Improved secretion of glycoproteins using an N-glycan-restricted passport sequence tag recognized by cargo receptor
MCFD2 and ERGIC-53, which are the products of causative genes of combined factor V and factor VIII deficiency, form a cargo receptor complex responsible for intracellular transport of these coagulation factors in the early secretory pathway. In this study, using an NMR technique, we successfully ide...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069976/ https://www.ncbi.nlm.nih.gov/pubmed/32170195 http://dx.doi.org/10.1038/s41467-020-15192-1 |