Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration

Microglia maintain brain homeostasis by removing neuron-derived components such as myelin and cell debris. The evidence linking microglia to neurodegenerative diseases is growing; however, the precise mechanisms remain poorly understood. Herein, we report a neuroprotective role for microglia in the...

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Detalles Bibliográficos
Autores principales: Choi, Insup, Zhang, Yuanxi, Seegobin, Steven P., Pruvost, Mathilde, Wang, Qian, Purtell, Kerry, Zhang, Bin, Yue, Zhenyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069981/
https://www.ncbi.nlm.nih.gov/pubmed/32170061
http://dx.doi.org/10.1038/s41467-020-15119-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069981/
https://www.ncbi.nlm.nih.gov/pubmed/32170061
http://dx.doi.org/10.1038/s41467-020-15119-w

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