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Profiling haplotype specific CpG and CpH methylation within a schizophrenia GWAS locus on chromosome 14 in schizophrenia and healthy subjects

Interrogating DNA methylation within schizophrenia risk loci holds promise to identify mechanisms by which genes influence the disease. Based on the hypothesis that allele specific methylation (ASM) of a single CpG, or perhaps CpH, might mediate or mark the effects of genetic variants on disease ris...

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Detalles Bibliográficos
Autores principales: Alfimova, Margarita, Kondratyev, Nikolay, Golov, Arkadiy, Golimbet, Vera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069985/
https://www.ncbi.nlm.nih.gov/pubmed/32170143
http://dx.doi.org/10.1038/s41598-020-61671-2