Small molecule regulated sgRNAs enable control of genome editing in E. coli by Cas9

CRISPR-Cas9 has led to great advances in gene editing for a broad spectrum of applications. To further the utility of Cas9 there have been efforts to achieve temporal control over its nuclease activity. While different approaches have focused on regulation of CRISPR interference or editing in mammal...

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Detalles Bibliográficos
Autores principales: Iwasaki, Roman S., Ozdilek, Bagdeser A., Garst, Andrew D., Choudhury, Alaksh, Batey, Robert T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070018/
https://www.ncbi.nlm.nih.gov/pubmed/32170140
http://dx.doi.org/10.1038/s41467-020-15226-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070018/
https://www.ncbi.nlm.nih.gov/pubmed/32170140
http://dx.doi.org/10.1038/s41467-020-15226-8

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