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Nucleosome positioning stability is a modulator of germline mutation rate variation across the human genome
Nucleosome organization has been suggested to affect local mutation rates in the genome. However, the lack of de novo mutation and high-resolution nucleosome data has limited the investigation of this hypothesis. Additionally, analyses using indirect mutation rate measurements have yielded contradic...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070026/ https://www.ncbi.nlm.nih.gov/pubmed/32170069 http://dx.doi.org/10.1038/s41467-020-15185-0 |