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Single-cell RNA sequencing reveals a heterogeneous response to Glucocorticoids in breast cancer cells

Steroid hormone receptors such as the Glucocorticoid Receptor (GR) mediate transcriptional responses to hormones and are frequently targeted in the treatment of human diseases. Experiments using bulk populations of cells have provided a detailed picture of the global transcriptional hormone response...

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Detalles Bibliográficos
Autores principales: Hoffman, Jackson A., Papas, Brian N., Trotter, Kevin W., Archer, Trevor K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070043/
https://www.ncbi.nlm.nih.gov/pubmed/32170217
http://dx.doi.org/10.1038/s42003-020-0837-0