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Establishment, optimisation and quantitation of a bioluminescent murine infection model of visceral leishmaniasis for systematic vaccine screening

Visceral leishmaniasis is an infectious parasitic disease caused by the protozoan parasites Leishmania donovani and Leishmania infantum. The drugs currently used to treat visceral leishmaniasis suffer from toxicity and the emergence of parasite resistance, and so a better solution would be the devel...

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Detalles Bibliográficos
Autores principales: Ong, Han Boon, Clare, Simon, Roberts, Adam Jonathan, Wilson, Mary Edythe, Wright, Gavin James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070049/
https://www.ncbi.nlm.nih.gov/pubmed/32170135
http://dx.doi.org/10.1038/s41598-020-61662-3