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“Iron free” zinc oxide nanoparticles with ion-leaking properties disrupt intracellular ROS and iron homeostasis to induce ferroptosis

Exposure to nanomaterials (NMs) is an emerging threat to human health, and the understanding of their intracellular behavior and related toxic effects is urgently needed. Ferroptosis is a newly discovered, iron-mediated cell death that is distinctive from apoptosis or other cell-death pathways. No e...

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Detalles Bibliográficos
Autores principales: Zhang, Changping, Liu, Zixuan, Zhang, Yuhao, Ma, Liang, Song, Erqun, Song, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070056/
https://www.ncbi.nlm.nih.gov/pubmed/32170066
http://dx.doi.org/10.1038/s41419-020-2384-5