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Cell cycle synchronisation using thiazolidinediones affects cellular glucose metabolism and enhances the therapeutic effect of 2-deoxyglucose in colon cancer

The effect of cell cycle synchronisation on glucose metabolism in cancer cells is not known. We assessed how cell cycle synchronisation by thiazolidinediones (TZDs) can affect glucose uptake by cancer cells and investigated the anti-cancer effect of combination therapy with TZDs and 2-deoxy-glucose...

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Detalles Bibliográficos
Autores principales: Yoon, Joon-Kee, Byeon, Hye Eun, Ko, Seung Ah, Park, Bok-Nam, An, Young-Sil, Lee, Ho-Young, Lee, Youn Woo, Lee, Su Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070066/
https://www.ncbi.nlm.nih.gov/pubmed/32170185
http://dx.doi.org/10.1038/s41598-020-61661-4