Cargando…

Accelerated identification of serine racemase inhibitor from Centella asiatica

Serine racemase (SR) converts the free form of L-serine into D-serine (DS) in the mammalian brain. The DS functions as a co-agonist of N-methyl D-aspartate (NMDA) receptor. The over- activation of NMDA receptor leads to many neurological disorders like stroke, amyotrophic lateral sclerosis, Alzheime...

Descripción completa

Detalles Bibliográficos
Autores principales: Rani, Komal, Tyagi, Mitali, Mazumder, Mohit, Singh, Akanksha, Shanmugam, Annaian, Dalal, Krishna, Pillai, Manoj, Samudrala, Gourinath, Kumar, Saroj, Srinivasan, Alagiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070078/
https://www.ncbi.nlm.nih.gov/pubmed/32170206
http://dx.doi.org/10.1038/s41598-020-61494-1