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Accelerated identification of serine racemase inhibitor from Centella asiatica

Serine racemase (SR) converts the free form of L-serine into D-serine (DS) in the mammalian brain. The DS functions as a co-agonist of N-methyl D-aspartate (NMDA) receptor. The over- activation of NMDA receptor leads to many neurological disorders like stroke, amyotrophic lateral sclerosis, Alzheime...

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Detalles Bibliográficos
Autores principales:	Rani, Komal, Tyagi, Mitali, Mazumder, Mohit, Singh, Akanksha, Shanmugam, Annaian, Dalal, Krishna, Pillai, Manoj, Samudrala, Gourinath, Kumar, Saroj, Srinivasan, Alagiri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070078/ https://www.ncbi.nlm.nih.gov/pubmed/32170206 http://dx.doi.org/10.1038/s41598-020-61494-1

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