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Circulating re-entrant waves promote maturation of hiPSC-derived cardiomyocytes in self-organized tissue ring

Directed differentiation methods allow acquisition of high-purity cardiomyocytes differentiated from human induced pluripotent stem cells (hiPSCs); however, their immaturity characteristic limits their application for drug screening and regenerative therapy. The rapid electrical pacing of cardiomyoc...

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Detalles Bibliográficos
Autores principales: Li, Junjun, Zhang, Lu, Yu, Leqian, Minami, Itsunari, Miyagawa, Shigeru, Hörning, Marcel, Dong, Ji, Qiao, Jing, Qu, Xiang, Hua, Ying, Fujimoto, Nanae, Shiba, Yuji, Zhao, Yang, Tang, Fuchou, Chen, Yong, Sawa, Yoshiki, Tang, Chao, Liu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070090/
https://www.ncbi.nlm.nih.gov/pubmed/32170165
http://dx.doi.org/10.1038/s42003-020-0853-0