Cell-type-specific role of CHK2 in mediating DNA damage-induced G2 cell cycle arrest

Cancer is a life-threatening disease that affects one in three people. Although most cases are sporadic, cancer risk can be increased by genetic factors. It remains unknown why certain genes predispose for specific forms of cancer only, such as checkpoint protein 2 (CHK2), in which gene mutations co...

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Detalles Bibliográficos
Autores principales: van Jaarsveld, Marijn T. M., Deng, Difan, Ordoñez-Rueda, Diana, Paulsen, Malte, Wiemer, Erik A. C., Zi, Zhike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070093/
https://www.ncbi.nlm.nih.gov/pubmed/32170104
http://dx.doi.org/10.1038/s41389-020-0219-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070093/
https://www.ncbi.nlm.nih.gov/pubmed/32170104
http://dx.doi.org/10.1038/s41389-020-0219-y

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