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Exploration of sensory and spinal neurons expressing gastrin-releasing peptide in itch and pain related behaviors

Gastrin-releasing peptide (GRP) functions as a neurotransmitter for non-histaminergic itch, but its site of action (sensory neurons vs spinal cord) remains controversial. To determine the role of GRP in sensory neurons, we generated a floxed Grp mouse line. We found that conditional knockout of Grp...

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Detalles Bibliográficos
Autores principales: Barry, Devin M., Liu, Xue-Ting, Liu, Benlong, Liu, Xian-Yu, Gao, Fang, Zeng, Xiansi, Liu, Juan, Yang, Qianyi, Wilhelm, Steven, Yin, Jun, Tao, Ailin, Chen, Zhou-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070094/
https://www.ncbi.nlm.nih.gov/pubmed/32170060
http://dx.doi.org/10.1038/s41467-020-15230-y