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Down-regulation of microRNA-203a suppresses IL-1β-induced inflammation and cartilage degradation in human chondrocytes through Smad3 signaling

Osteoarthritis (OA) is a chronic and prevalent degenerative musculoskeletal disorder, which is characterized by articular cartilage degradation and joint inflammation. MicroRNA-203a (miR-203a) has been shown to be involved in multiple pathological processes during OA, but little is known about its f...

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Detalles Bibliográficos
Autores principales: An, Yongbo, Wan, Guang, Tao, Jingang, Cui, Mingxing, Zhou, Qinglan, Hou, Wengen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070148/
https://www.ncbi.nlm.nih.gov/pubmed/32083281
http://dx.doi.org/10.1042/BSR20192723