Hydrogen Peroxide Mediates Artemisinin-Derived C-16 Carba-Dimer-Induced Toxicity of Human Cancer Cells

This study used a nitroaliphatic chemistry approach to synthesize a novel artemisinin-derived carba-dimer (AG-1) and determined its anti-proliferative effects in human normal and cancer cells. AG-1 treatments selectively inhibit proliferation of cancer cells compared to normal human fibroblasts. Com...

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Detalles Bibliográficos
Autores principales: Kalen, Amanda L., Wagner, Brett A., Sarsour, Ehab H., Kumar, Maneesh G., Reedy, Jessica L., Buettner, Garry R., Barua, Nabin C., Goswami, Prabhat C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070254/
https://www.ncbi.nlm.nih.gov/pubmed/31991904
http://dx.doi.org/10.3390/antiox9020108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070254/
https://www.ncbi.nlm.nih.gov/pubmed/31991904
http://dx.doi.org/10.3390/antiox9020108

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