Polyurea Dendrimer Folate-Targeted Nanodelivery of l-Buthionine Sulfoximine as a Tool to Tackle Ovarian Cancer Chemoresistance

Ovarian cancer is a highly lethal disease, mainly due to chemoresistance. Our previous studies on metabolic remodeling in ovarian cancer have supported that the reliance on glutathione (GSH) bioavailability is a main adaptive metabolic mechanism, also accounting for chemoresistance to conventional t...

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Detalles Bibliográficos
Autores principales: Cruz, Adriana, Mota, Pedro, Ramos, Cristiano, Pires, Rita F., Mendes, Cindy, Silva, José P., Nunes, Sofia C., Bonifácio, Vasco D. B., Serpa, Jacinta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070262/
https://www.ncbi.nlm.nih.gov/pubmed/32028640
http://dx.doi.org/10.3390/antiox9020133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070262/
https://www.ncbi.nlm.nih.gov/pubmed/32028640
http://dx.doi.org/10.3390/antiox9020133

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