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Polyurea Dendrimer Folate-Targeted Nanodelivery of l-Buthionine Sulfoximine as a Tool to Tackle Ovarian Cancer Chemoresistance
Ovarian cancer is a highly lethal disease, mainly due to chemoresistance. Our previous studies on metabolic remodeling in ovarian cancer have supported that the reliance on glutathione (GSH) bioavailability is a main adaptive metabolic mechanism, also accounting for chemoresistance to conventional t...
Autores principales: | Cruz, Adriana, Mota, Pedro, Ramos, Cristiano, Pires, Rita F., Mendes, Cindy, Silva, José P., Nunes, Sofia C., Bonifácio, Vasco D. B., Serpa, Jacinta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070262/ https://www.ncbi.nlm.nih.gov/pubmed/32028640 http://dx.doi.org/10.3390/antiox9020133 |
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