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Effect of Copper on the Mitochondrial Carnitine/Acylcarnitine Carrier Via Interaction with Cys136 and Cys155. Possible Implications in Pathophysiology

The effect of copper on the mitochondrial carnitine/acylcarnitine carrier (CAC) was studied. Transport function was assayed as [(3)H]carnitine/carnitine antiport in proteoliposomes reconstituted with the native protein extracted from rat liver mitochondria or with the recombinant CAC over-expressed...

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Detalles Bibliográficos
Autores principales: Giangregorio, Nicola, Tonazzi, Annamaria, Console, Lara, Prejanò, Mario, Marino, Tiziana, Russo, Nino, Indiveri, Cesare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070283/
https://www.ncbi.nlm.nih.gov/pubmed/32070004
http://dx.doi.org/10.3390/molecules25040820